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Getting to the root of ashwagandha

Last Modified: October 10, 2024

Family Medicine

This post was written by Shivani Bhakta, PharmD, BCACP, Parkview Health.

The public's interest in dietary supplements has surged over the past decade, leading to the introduction of a wide variety of available products to support health and well-being. Among these is ashwagandha, an herb praised for its potential benefits in reducing stress and inflammation.

What is ashwagandha?

Ashwagandha, also known as the Indian winter cherry, is a shrub native to parts of India, the Middle East and Africa. Practitioners of homeopathic medicine often use the plant's roots for its therapeutic effects. Though not approved for the treatment of any medical condition, manufacturers advertise the supplement as helping with inflammation, stress relief and brain health.
 

Benefits

The most studied component of this supplement is withanolides. These naturally occurring steroids exhibit anti-inflammatory and antioxidant properties by inhibiting the production of inflammatory markers in the body. This process may contribute to:

  • Increased immunity - By reducing inflammation, ashwagandha may help strengthen the body's natural defenses against infections and illness.

  • Stress relief - Ashwagandha helps lower the production of cortisol, the body's primary stress hormone, which can lead to reduced stress and anxiety levels.

  • Brain health - The herb's antioxidant properties may protect nerves and support the growth of new nerve cells, potentially enhancing cognitive function and overall brain health.

Some small studies suggest that ashwagandha may be beneficial in conditions such as Alzheimer's disease, but there is not enough data to support these claims fully.
 

Precautions

While ashwagandha offers a range of potential health benefits, it is essential to be aware of possible side effects and interactions. Some individuals may experience:

  • Drowsiness

  • Upset stomach

  • Diarrhea

  • Vomiting

Additionally, certain people may be at risk of experiencing adverse complications as a result of pre-existing medical conditions. Individuals in the following groups should avoid ashwagandha:

Final thoughts

Although ashwagandha's properties make it potentially effective in lowering stress and inflammation and improving overall well-being, as with any supplement, it's essential to approach its use with caution. Keep in mind that this herb is not a treatment for any specific medical condition, and results may vary from person to person. Always consult with a healthcare provider or pharmacist before beginning use, especially for individuals living with chronic health conditions or those taking other medications.

If you have questions about ashwagandha or other medications and supplements, Parkview Outpatient Pharmacies is here to help. We are committed to exceptional service and work directly with your doctor to ensure medication appropriateness and safety. Contact your preferred Parkview outpatient pharmacy, and our staff will gladly assist you with questions or prescription transfers.

 

 

 

 

References:

Mikulska P, Malinowska M, Ignacyk M, et al. Ashwagandha (Withania somnifera)-Current Research on the Health-Promoting Activities: A Narrative Review. Pharmaceutics. 2023;15(4):1057. Published 2023 Mar 24. doi:10.3390/pharmaceutics15041057

Ashwagandha: Usefulness and safety. National Center for Complementary and Integrative Health. 2023. https://www.nccih.nih.gov/health/ashwagandha

Djaoudene O, Romano A, Bradai YD, et al. A Global Overview of Dietary Supplements: Regulation, Market Trends, Usage during the COVID-19 Pandemic, and Health Effects. Nutrients. 2023;15(15):3320. Published 2023 Jul 26. doi:10.3390/nu15153320